In Woman Or Merry Man With Sexual of the Shingles, Aciclovir does Not Prevent Aquisition HIV
Aciclovir, Antivirusnoe medicine, does not reduce the issue HIV-1 in woman or man, who have a herpes carnal, that has a sex with man, according to author of the Article free in June 20, 2008 in Lancet.
The Simplex virus of the Shingles type-2 infections (HSV-2), most general reason of the shingles animal, is bound two on three-pack the increased risk to infections HIV-1. To help to define the nature to this assotiations, Dr. Connie Celum, University Washington, Seattle, USA, and colleagues, studied effects of the suppression HSV-2 with aciclovir on HIV-1. This was made using negative HIV-, positive women(woman)s HSV-2 in continent and man, who have a sex with man (MSM) with places in Peru and USA.
In mixed, operated by phase III test, participants have ing appointed to be control 400mg aciclovir (1,637 patients) or (1,640 patients) during 12-18 months. Followups whir Executed monthly to study the distribution a medicine analysis, execute the counsel of the devotion, add up of the pill (itself registered), and reduction barrister of the risk. Each three months, examinations propagative and test HIV were executed. The Tested results be an infection HIV-1 and and canker sexual HSV-2.
The Participants were 1,358 womans and 1,814 MSM comprised of analysis: 1,581 in group aciclovir and 1,591 in controlling gruppe. incidence HIV-1 was not vastly another between group. This said, occurrence gentical cankers reducted to 47% in group aciclovir, and 65% cankers physical confirmed to be suitable to HSV-2. Was Not no serious disadvantage event in transcribed drug.
In conclusion, authors tell that aciclovir have an no influence in factor of the issue HIV-1 in this population. “Our results show that repressing therapy with standard dose aciclovir not efficient inn reduction of aquisition HIV-1 in HSV-2 seropositive wife and MSM. The New strategies - it is life-and-death to break the interaction between HSV-2 and HIV-1.” Additionally, speak, these futher studies must be executed to install independently this defect to efficiency is due to absorptions medicine and metabolism, clinical answer of the cankers sexual in medicine, or proprietorship answer concern sexual rear HSV-2 will is actuated.
The Professor Ronald Gray and Weaver Professor Maria, John Hopkins University, Baltimore, MD, USA, accompanying commentary in pron they converse about if management sexual send infection must be advanced for forbidding HIV in pessimistic citizenry retrovirus. “Thomas Henry Huxley commented that ‘ big calamity of the science - a murder of the beautiful hypothesis by ugly fact.’ The Time to revalue the hypothesis and two adjust the policy of the prevention accordingly.”
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